Explore Options

If it isn’t “just happening,” get help. A fertility specialist (a Reproductive Endocrinologist) can identify issues in both men and women and move you forward on your path to a larger family. Some common advanced fertility treatments for women are explored below.

85-90% of infertile couples in treatment do not require IVF 54

ART

Assisted Reproductive Technology (ART) is an umbrella term that includes all fertility treatments in which both eggs and sperm are handled. In general, ART procedures involve surgically removing eggs from a woman’s ovaries, combining them with sperm in the laboratory, and returning them to the woman’s body or donating them to another woman.55

Types of ART

  • In vitro fertilization (IVF)
  • Intracytoplasmic sperm injection (ICSI)
  • Assisted hatching
  • Frozen embryo transfer (FET)
  • Third-party assisted ART is a more advanced option56
    • Sperm donation
    • Egg donation
    • Surrogates and gestational carriers

Your fertility specialist (a Reproductive Endocrinologist) will work with you to find the right treatment for you.

IVF

In vitro fertilization (IVF) is the most common ART procedure. During IVF, medications are often used to stimulate the development and release of a woman’s eggs. The eggs and sperm are then collected and placed together in a laboratory dish to fertilize.57 If the eggs are successfully fertilized, one or some of the resulting embryos are transferred into a woman’s uterus. The goal is that one of the fertilized eggs will implant and begin to develop. Any embryos not transferred may be frozen for later use.

In reciprocal IVF, also known as IVF with embryo transfer, the procedure is performed using the eggs of one partner and the womb of the other. For lesbian couples, reciprocal IVF can help both women feel an equal biological tie to the child.58

OI

Ovulation Induction (OI) may be considered if fertility testing shows there’s an ovulatory problem and your body could use help inducing follicle development and ovulation.

If your fertility specialist thinks you or your partner are not ovulating regularly, ovulating early, or are late in your cycle, you’re not alone. Fertility medications controlling ovulation are prescribed on their own, or as an integrated regimen.

Medications for ART (Including IVF) and/or OI

Gonal-f® (follitropin alfa for injection) is taken during the follicular phase supplements or replaces a woman's natural supply of follicle-stimulating hormone (FSH). In OI, it helps stimulate the maturation of one egg. In IVF, it helps multiple egg-containing follicles in the ovary mature. Learn More 

Full Prescribing Information for Gonal-f® RFF* Redi-Ject®, Gonal-f® RFF* and Gonal-f® Multi-Dose

Cetrotide® (cetrorelix acetate for injection) may be used in controlled ovarian stimulation during IVF (ART). Throughout the cycle, a woman's body releases a hormone called estradiol. If the level of estradiol gets too high too early, it can trigger a premature surge of luteinizing hormone (LH), which leads to early ovulation. Cetrotide® may be used to delay this surge until the developing follicles are ready. Learn More

Please see Important Risk Information and Full Prescribing Information for Cetrotide®.

Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection) mimics the surge of LH, which triggers the final step in the follicular phase. For ovulation induction, the hormone in Ovidrel® is used for final egg maturation as part of the final process of releasing the egg. For IVF, Ovidrel® is used for final egg maturation on eggs that will be collected prior to ovulation. Learn More 

Please see Important Risk Information and Full Prescribing Information for Ovidrel®.

54

American Society for Reproductive Medicine, Quick Facts About Infertility, accessed July 2016

56

ASRM, Third-Party Reproduction, 2012

57

RESOLVE, IVF/ART, 2013

58

Pelka S. J Homosex. 2009;56:195-217.

IMPORTANT RISK INFORMATION AND INDICATION

Do not use Gonal-f® RFF* Redi-ject® (follitropin alfa injection) if you:

  • are allergic to recombinant human FSH or any of the ingredients listed here:  follitropin alfa (r-hFSH), sucrose, meta-cresol, di-sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate monohydrate, methionine, Poloxamer 188, O-phosphoric acid, sodium hydroxide
  • have ovaries that no longer make eggs (primary ovarian failure)
  • are pregnant or think you may be pregnant
  • have uncontrolled thyroid or adrenal problems
  • have a tumor in your female organs, including your ovaries, breast, or uterus
  • have a tumor in your brain, such as a tumor in your pituitary or hypothalamus
  • have abnormal bleeding from your uterus or vagina
  • have ovarian cysts or large ovaries, not due to polycystic ovary syndrome (PCOS)

Before you use Gonal-f® RFF* Redi-ject®, tell your healthcare provider if you:

  • have or have had asthma
  • have been told by a healthcare provider that you have an increased risk for blood clots (thrombosis)
  • have ever had a blood clot (thrombosis), or anyone in your family has ever had a blood clot (thrombosis)
  • have had abdominal surgery
  • have had twisting of your ovary (ovarian torsion)
  • had or have a cyst on your ovary
  • have polycystic ovarian disease
  • have any other medical conditions
  • are breastfeeding or plan to breastfeed
  • are taking any other prescription or over-the-counter medicines, vitamins, and herbal supplements

Gonal-f® RFF* Redi-ject® may cause serious side effects, including:

  • severe allergic reactions in women who have used Gonal-f®, Gonal-f® RFF*, or Gonal-f® RFF* Redi-ject® in the past.  New allergic reactions can occur immediately after an injection.  Severe allergic reaction may lead to death. If you have any of the following symptoms of a severe allergic reaction, stop using Gonal-f® RFF* Redi-ject® and go to the hospital right away:
    • shortness of breath
    • swelling of your face
    • itchy, red bumps or rash on your skin (hives)
  • ovaries that are too large; symptoms of bloating or pain in your lower stomach (pelvic) area.
  • ovarian hyperstimulation syndrome (OHSS); a serious medical condition that can happen when your ovaries produce too many eggs (overstimulated). OHSS can cause fluid to suddenly build up in the area of your stomach, chest, and heart, and can cause blood clots to form. In rare cases OHSS has caused death. OHSS may also happen after you stop using Gonal-f® RFFRedi-ject®.  Stop using Gonal-f® RFF* Redi-ject® and call your healthcare provider right away if you have symptoms of OHSS, including:
    • trouble breathing
    • severe lower stomach (pelvic) area pain
    • decreased urine output
    • nausea
    • vomiting
    • weight gain
    • diarrhea
  • lung problems; that cause trouble breathing (acute respiratory distress syndrome, atelectasia) and worsening of asthma.
  • blood clots can cause:
    • blood vessel problems (thrombophlebitis)
    • stroke
    • loss of your arm or leg
    • blood clot in your lung (pulmonary embolism)
  • twisting (torsion) of your ovary if you already have certain conditions such as ovarian cysts, OHSS, pregnancy and previous abdominal surgery. Twisting of your ovary may lead to blood flow being cut off to your ovary.
  • pregnancy with more than 1 baby and birth of multiple babies; Having a pregnancy and giving birth to multiple babies at a time increases the health risk for you and your babies. Your healthcare provider should tell you about your chances of multiple births.
  • birth defects in a baby born after an ART cycle (IVF or ICSI).  Your chances of having a baby with birth defects may increase depending on:
    • your age
    • certain sperm problems
    • your genetic background and that of your partner
    • a pregnancy with more than 1 baby at a time
  • ectopic pregnancy (pregnancy outside your womb). Your chance of having a pregnancy outside of your womb is increased if you also have fallopian tube problems.
  • miscarriage. Your chance of loss of an early pregnancy may be increased if you had difficulty becoming pregnant.
  • tumors of the ovary. If you have used fertility medicines like Gonal-f® RFF* Redi-ject® (follitropin alfa injection) before to get pregnant, you may have an increased chance of having tumors in your ovary(ies) (including cancer).

The most common side effects of Gonal-f® RFF* Redi-ject® include:

  • headache
  • stomach pain
  • stomach bloating
  • bruising at the injection site
  • nausea

These are not all the possible side effects of Gonal-f® RFF* Redi-ject®. For more information, call your healthcare provider or pharmacist. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Do not share your Gonal-f® RFF* Redi-ject® and needles with another person. You may give another person an infection or get an infection from them.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Also read the Gonal-f® RFF* Redi-ject® “Instructions for Use” that comes with Pen for information about the correct use of Gonal-f® RFF* Redi-ject® and follow all training and instruction provided by your healthcare provider.

Gonal-f® RFF* Redi-ject® is an injection Pen that delivers a prescription medicine containing follicle-stimulating hormone (FSH) used in infertile women to:

  • help healthy ovaries develop (mature) and release an egg
  • cause your ovaries to make multiple (more than 1) eggs as part of an Assisted Reproductive Technology (ART) program

*RFF, Revised Formulation Female


IMPORTANT RISK INFORMATION AND INDICATION

Who should not use Gonal-f® (follitropin alfa for injection) and Gonal-f® RFF* (follitropin alfa for injection)?

Gonal-f® Multi-Dose and Gonal-f® RFF* should not be used in patients who are pregnant or think they might be pregnant, in patients with primary ovarian failure (the ovaries no longer produce eggs), or in patients with allergies to recombinant human FSH products or any other ingredients in the medication.

Patients with cancer of the sex organs or brain, or with uncontrolled thyroid or adrenal disease, should not use Gonal-f® Multi-Dose or Gonal-f® RFF*. Women with a history of abnormal bleeding from the uterus or vagina or with swollen, enlarged, or painful ovaries should speak to their doctor before starting treatment.

What are the possible side effects of Gonal-f® and Gonal-f® RFF*?

The lowest dose expected to achieve the desired results should be used. A doctor should monitor a woman’s response often to avoid overdose, which can lead to serious side effects, including blood clots.

Women should contact their doctor if severe pain or bloating in the stomach or pelvic area, severe upset stomach, vomiting, or weight gain are experienced during treatment. These could be signs of a rare but serious condition known as Ovarian Hyperstimulation Syndrome, or OHSS, which can result in hospitalization.

Use of Gonal-f® Multi-Dose or Gonal-f® RFF* by a woman can be associated with fertilization of more than 1 egg. This can lead to complications for the woman and the birth of 2 or more babies.

The most common side effects reported by women were headache, ovarian cysts, upset stomach, and sinus infection. The most common side effects reported by men taking Gonal-f® Multi-Dose were skin pimples, breast pain and growth, and tiredness. Injections may cause some discomfort.

What are the uses of Gonal-f® (follitropin alfa for injection) and Gonal-f® RFF* (follitropin alfa for injection)?

Gonal-f® Multi-Dose and Gonal-f® RFF* are 2 products that contain follitropin alfa, which is similar to the human hormone follicle-stimulating hormone, referred to as FSH. FSH belongs to a group of human reproductive hormones.

Gonal-f® Multi-Dose and Gonal-f® RFF* are used in certain infertile women to help with ovulation (production and release of a mature egg) and pregnancy. Gonal-f® will not help women whose ovaries no longer work because of a condition called Primary Ovarian Failure. Gonal-f® may also be used in women who are in an Assisted Reproductive Technology (ART) program such as in vitro fertilization to help their ovaries make more eggs.

Gonal-f® Multi-Dose can also be prescribed to increase sperm production in men with a rare condition that affects sperm production.

Both products should be prescribed only by doctors specializing in infertility problems and their treatment.

*RFF, Revised Formulation Female


IMPORTANT RISK INFORMATION AND INDICATION

Who should not use Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection)?

Ovidrel® PreFilled Syringe should not be used in patients who are pregnant or breastfeeding, in patients with primary ovarian failure (the ovaries no longer produce eggs), or in patients with allergies to hCG or any other ingredients in the medication.

Patients with cancer of the sex organs or brain, or with uncontrolled thyroid or adrenal disease, should not use Ovidrel® PreFilled Syringe. Women with a history of abnormal bleeding from the uterus or vagina or with swollen, enlarged, or painful ovaries should speak to their doctor before starting treatment.

In infertile women undergoing assisted reproductive technologies (ART) and ovulation induction (OI), Ovidrel® PreFilled Syringe should not be administered until adequate follicular development is indicated by serum estradiol and vaginal ultrasonography.

Ovidrel® PreFilled Syringe administration should be withheld in situations where there is an excessive ovarian response, as evidenced by multiple follicular development, clinically significant ovarian enlargement or excessive estradiol production.

What are the possible side effects of Ovidrel® PreFilled Syringe?

Your doctor should review with you the risks and benefits of using Ovidrel® PreFilled Syringe. As with any medication, report any and all side effects, symptoms, or physical changes to your doctor.

Ovidrel® PreFilled Syringe can cause serious side effects including ovarian hyperstimulation syndrome (OHSS) and lung and blood vessel problems. Contact your healthcare provider if you experience severe pain or bloating in the stomach or pelvic area, severe upset stomach, vomiting, or weight gain.

Use of fertility drugs can be associated with fertilization of more than one egg. This can lead to complications for the mother and the birth of two or more babies.

The most common side effects in women using Ovidrel® PreFilled Syringe include abdominal pain, nausea, and vomiting. Needle injections may cause some discomfort.

What are the uses of Ovidrel® PreFilled Syringe?
Ovidrel® PreFilled Syringe contains recombinant human choriogonadotropin alfa (hCG), an injectable hormone. This is the hormone that causes your eggs to finish maturing and be released. You may be given Ovidrel® PreFilled Syringe to complete this final stage of your cycle. Doctors specializing in infertility or reproductive health prescribe Ovidrel® PreFilled Syringe to those women trying to have a child but for a variety of reasons need medical assistance. After a thorough medical exam to determine your specific medical condition, your doctor may prescribe Ovidrel® PreFilled Syringe because you require hormone replacement or supplementation as part of your treatment program. Ovidrel® PreFilled Syringe may be one of several drugs prescribed to a patient as part of a treatment program.


IMPORTANT RISK INFORMATION AND INDICATION

Who should not use Cetrotide® (cetrorelix acetate for injection)?

Cetrotide® should not be used in patients who are pregnant, think they might be pregnant, or are breastfeeding.

Cetrotide® should not be used in patients with kidney disease.

Patients that are allergic to cetrorelix acetate, mannitol, or exogenous peptide hormones – medicines similar to Cetrotide®-should not use Cetrotide®. Consult your doctor before taking Cetrotide® if you have had severe allergic reactions.

What are the possible side effects of Cetrotide®?

Your doctor should review with you the risks and benefits of using Cetrotide®. As with any medication, report any and all side effects, symptoms, or physical changes to your doctor.

Mild and short-lasting reactions may occur at the injection site like reddening, itching, and swelling. Nausea and headache have also been reported.

Call your doctor if you have any other side effect or if you are unsure about the effect of this medicine.

What are the uses of Cetrotide®?

Cetrotide® blocks the effects of a natural hormone, called gonadotropin-releasing hormone (GnRH). GnRH controls the secretion of another hormone, called luteinizing hormone (LH), which induces ovulation during the menstrual cycle.

During hormone treatment for ovarian stimulation, premature ovulation may lead to eggs that are not suitable for fertilization. Cetrotide® blocks such undesirable premature ovulation.


© 2017 EMD Serono, Inc. and its affiliates.

This site contains medical information that is intended for residents of the United States only and is not meant to substitute for the advice provided by a medical professional. Always consult a physician if you have health concerns. Use and access of this site is subject to the terms and conditions as set out in our Legal Statement and Privacy Policy.

 

IMPORTANT RISK INFORMATION AND INDICATION

Do not use Gonal-f® RFF* Redi-ject® (follitropin alfa injection) if you:

  • are allergic to recombinant human FSH or any of the ingredients listed here:  follitropin alfa (r-hFSH), sucrose, meta-cresol, di-sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate monohydrate, methionine, Poloxamer 188, O-phosphoric acid, sodium hydroxide
  • have ovaries that no longer make eggs (primary ovarian failure)
  • are pregnant or think you may be pregnant
  • have uncontrolled thyroid or adrenal problems
  • have a tumor in your female organs, including your ovaries, breast, or uterus
  • have a tumor in your brain, such as a tumor in your pituitary or hypothalamus
  • have abnormal bleeding from your uterus or vagina
  • have ovarian cysts or large ovaries, not due to polycystic ovary syndrome (PCOS)

Before you use Gonal-f® RFF* Redi-ject®, tell your healthcare provider if you:

  • have or have had asthma
  • have been told by a healthcare provider that you have an increased risk for blood clots (thrombosis)
  • have ever had a blood clot (thrombosis), or anyone in your family has ever had a blood clot (thrombosis)
  • have had abdominal surgery
  • have had twisting of your ovary (ovarian torsion)
  • had or have a cyst on your ovary
  • have polycystic ovarian disease
  • have any other medical conditions
  • are breastfeeding or plan to breastfeed
  • are taking any other prescription or over-the-counter medicines, vitamins, and herbal supplements

Gonal-f® RFF* Redi-ject® may cause serious side effects, including:

  • severe allergic reactions in women who have used Gonal-f®, Gonal-f® RFF*, or Gonal-f® RFF* Redi-ject® in the past.  New allergic reactions can occur immediately after an injection.  Severe allergic reaction may lead to death. If you have any of the following symptoms of a severe allergic reaction, stop using Gonal-f® RFF* Redi-ject® and go to the hospital right away:
    • shortness of breath
    • swelling of your face
    • itchy, red bumps or rash on your skin (hives)
  • ovaries that are too large; symptoms of bloating or pain in your lower stomach (pelvic) area.
  • ovarian hyperstimulation syndrome (OHSS); a serious medical condition that can happen when your ovaries produce too many eggs (overstimulated). OHSS can cause fluid to suddenly build up in the area of your stomach, chest, and heart, and can cause blood clots to form. In rare cases OHSS has caused death. OHSS may also happen after you stop using Gonal-f® RFFRedi-ject®.  Stop using Gonal-f® RFF* Redi-ject® and call your healthcare provider right away if you have symptoms of OHSS, including:
    • trouble breathing
    • severe lower stomach (pelvic) area pain
    • decreased urine output
    • nausea
    • vomiting
    • weight gain
    • diarrhea
  • lung problems; that cause trouble breathing (acute respiratory distress syndrome, atelectasia) and worsening of asthma.
  • blood clots can cause:
    • blood vessel problems (thrombophlebitis)
    • stroke
    • loss of your arm or leg
    • blood clot in your lung (pulmonary embolism)
  • twisting (torsion) of your ovary if you already have certain conditions such as ovarian cysts, OHSS, pregnancy and previous abdominal surgery. Twisting of your ovary may lead to blood flow being cut off to your ovary.
  • pregnancy with more than 1 baby and birth of multiple babies; Having a pregnancy and giving birth to multiple babies at a time increases the health risk for you and your babies. Your healthcare provider should tell you about your chances of multiple births.
  • birth defects in a baby born after an ART cycle (IVF or ICSI).  Your chances of having a baby with birth defects may increase depending on:
    • your age
    • certain sperm problems
    • your genetic background and that of your partner
    • a pregnancy with more than 1 baby at a time
  • ectopic pregnancy (pregnancy outside your womb). Your chance of having a pregnancy outside of your womb is increased if you also have fallopian tube problems.
  • miscarriage. Your chance of loss of an early pregnancy may be increased if you had difficulty becoming pregnant.
  • tumors of the ovary. If you have used fertility medicines like Gonal-f® RFF* Redi-ject® (follitropin alfa injection) before to get pregnant, you may have an increased chance of having tumors in your ovary(ies) (including cancer).

The most common side effects of Gonal-f® RFF* Redi-ject® include:

  • headache
  • stomach pain
  • stomach bloating
  • bruising at the injection site
  • nausea

These are not all the possible side effects of Gonal-f® RFF* Redi-ject®. For more information, call your healthcare provider or pharmacist. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Do not share your Gonal-f® RFF* Redi-ject® and needles with another person. You may give another person an infection or get an infection from them.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Also read the Gonal-f® RFF* Redi-ject® “Instructions for Use” that comes with Pen for information about the correct use of Gonal-f® RFF* Redi-ject® and follow all training and instruction provided by your healthcare provider.

Gonal-f® RFF* Redi-ject® is an injection Pen that delivers a prescription medicine containing follicle-stimulating hormone (FSH) used in infertile women to:

  • help healthy ovaries develop (mature) and release an egg
  • cause your ovaries to make multiple (more than 1) eggs as part of an Assisted Reproductive Technology (ART) program

*RFF, Revised Formulation Female


IMPORTANT RISK INFORMATION AND INDICATION

Who should not use Gonal-f® (follitropin alfa for injection) and Gonal-f® RFF* (follitropin alfa for injection)?

Gonal-f® Multi-Dose and Gonal-f® RFF* should not be used in patients who are pregnant or think they might be pregnant, in patients with primary ovarian failure (the ovaries no longer produce eggs), or in patients with allergies to recombinant human FSH products or any other ingredients in the medication.

Patients with cancer of the sex organs or brain, or with uncontrolled thyroid or adrenal disease, should not use Gonal-f® Multi-Dose or Gonal-f® RFF*. Women with a history of abnormal bleeding from the uterus or vagina or with swollen, enlarged, or painful ovaries should speak to their doctor before starting treatment.

What are the possible side effects of Gonal-f® and Gonal-f® RFF*?

The lowest dose expected to achieve the desired results should be used. A doctor should monitor a woman’s response often to avoid overdose, which can lead to serious side effects, including blood clots.

Women should contact their doctor if severe pain or bloating in the stomach or pelvic area, severe upset stomach, vomiting, or weight gain are experienced during treatment. These could be signs of a rare but serious condition known as Ovarian Hyperstimulation Syndrome, or OHSS, which can result in hospitalization.

Use of Gonal-f® Multi-Dose or Gonal-f® RFF* by a woman can be associated with fertilization of more than 1 egg. This can lead to complications for the woman and the birth of 2 or more babies.

The most common side effects reported by women were headache, ovarian cysts, upset stomach, and sinus infection. The most common side effects reported by men taking Gonal-f® Multi-Dose were skin pimples, breast pain and growth, and tiredness. Injections may cause some discomfort.

What are the uses of Gonal-f® (follitropin alfa for injection) and Gonal-f® RFF* (follitropin alfa for injection)?

Gonal-f® Multi-Dose and Gonal-f® RFF* are 2 products that contain follitropin alfa, which is similar to the human hormone follicle-stimulating hormone, referred to as FSH. FSH belongs to a group of human reproductive hormones.

Gonal-f® Multi-Dose and Gonal-f® RFF* are used in certain infertile women to help with ovulation (production and release of a mature egg) and pregnancy. Gonal-f® will not help women whose ovaries no longer work because of a condition called Primary Ovarian Failure. Gonal-f® may also be used in women who are in an Assisted Reproductive Technology (ART) program such as in vitro fertilization to help their ovaries make more eggs.

Gonal-f® Multi-Dose can also be prescribed to increase sperm production in men with a rare condition that affects sperm production.

Both products should be prescribed only by doctors specializing in infertility problems and their treatment.

*RFF, Revised Formulation Female


IMPORTANT RISK INFORMATION AND INDICATION

Who should not use Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection)?

Ovidrel® PreFilled Syringe should not be used in patients who are pregnant or breastfeeding, in patients with primary ovarian failure (the ovaries no longer produce eggs), or in patients with allergies to hCG or any other ingredients in the medication.

Patients with cancer of the sex organs or brain, or with uncontrolled thyroid or adrenal disease, should not use Ovidrel® PreFilled Syringe. Women with a history of abnormal bleeding from the uterus or vagina or with swollen, enlarged, or painful ovaries should speak to their doctor before starting treatment.

In infertile women undergoing assisted reproductive technologies (ART) and ovulation induction (OI), Ovidrel® PreFilled Syringe should not be administered until adequate follicular development is indicated by serum estradiol and vaginal ultrasonography.

Ovidrel® PreFilled Syringe administration should be withheld in situations where there is an excessive ovarian response, as evidenced by multiple follicular development, clinically significant ovarian enlargement or excessive estradiol production.

What are the possible side effects of Ovidrel® PreFilled Syringe?

Your doctor should review with you the risks and benefits of using Ovidrel® PreFilled Syringe. As with any medication, report any and all side effects, symptoms, or physical changes to your doctor.

Ovidrel® PreFilled Syringe can cause serious side effects including ovarian hyperstimulation syndrome (OHSS) and lung and blood vessel problems. Contact your healthcare provider if you experience severe pain or bloating in the stomach or pelvic area, severe upset stomach, vomiting, or weight gain.

Use of fertility drugs can be associated with fertilization of more than one egg. This can lead to complications for the mother and the birth of two or more babies.

The most common side effects in women using Ovidrel® PreFilled Syringe include abdominal pain, nausea, and vomiting. Needle injections may cause some discomfort.

What are the uses of Ovidrel® PreFilled Syringe?
Ovidrel® PreFilled Syringe contains recombinant human choriogonadotropin alfa (hCG), an injectable hormone. This is the hormone that causes your eggs to finish maturing and be released. You may be given Ovidrel® PreFilled Syringe to complete this final stage of your cycle. Doctors specializing in infertility or reproductive health prescribe Ovidrel® PreFilled Syringe to those women trying to have a child but for a variety of reasons need medical assistance. After a thorough medical exam to determine your specific medical condition, your doctor may prescribe Ovidrel® PreFilled Syringe because you require hormone replacement or supplementation as part of your treatment program. Ovidrel® PreFilled Syringe may be one of several drugs prescribed to a patient as part of a treatment program.


IMPORTANT RISK INFORMATION AND INDICATION

Who should not use Cetrotide® (cetrorelix acetate for injection)?

Cetrotide® should not be used in patients who are pregnant, think they might be pregnant, or are breastfeeding.

Cetrotide® should not be used in patients with kidney disease.

Patients that are allergic to cetrorelix acetate, mannitol, or exogenous peptide hormones – medicines similar to Cetrotide®-should not use Cetrotide®. Consult your doctor before taking Cetrotide® if you have had severe allergic reactions.

What are the possible side effects of Cetrotide®?

Your doctor should review with you the risks and benefits of using Cetrotide®. As with any medication, report any and all side effects, symptoms, or physical changes to your doctor.

Mild and short-lasting reactions may occur at the injection site like reddening, itching, and swelling. Nausea and headache have also been reported.

Call your doctor if you have any other side effect or if you are unsure about the effect of this medicine.

What are the uses of Cetrotide®?

Cetrotide® blocks the effects of a natural hormone, called gonadotropin-releasing hormone (GnRH). GnRH controls the secretion of another hormone, called luteinizing hormone (LH), which induces ovulation during the menstrual cycle.

During hormone treatment for ovarian stimulation, premature ovulation may lead to eggs that are not suitable for fertilization. Cetrotide® blocks such undesirable premature ovulation.


© 2017 EMD Serono, Inc. and its affiliates.

This site contains medical information that is intended for residents of the United States only and is not meant to substitute for the advice provided by a medical professional. Always consult a physician if you have health concerns. Use and access of this site is subject to the terms and conditions as set out in our Legal Statement and Privacy Policy.